Theophylline anhydrous

Theophylline anhydrous
(Antiasthmatic & COPD Preparations)

Dosage form	Brand	Strength
tablet	Almarion®	125 mg

Indication : Tx of symptoms and reversible airway obstruction due to chronic asthma, or other chronic lung diseases

Mechanism of action : blocking phosphodiesterase which increases tissue concentrations of cAMP

Pregnancy Category C

Contraindication : Hypersensitivity to theophylline, patients with allergy to corn-related products                                                                      

Precaution : Cardiovascular disease, Hyperthyroidism, Peptic ulcer diseases

Drug Interaction : Adenosine, Benzodiazepines, Beta blocking

Side Effect : Flutter, tachycardia Headache, hyperactivity (children), insomnia, restlessness, seizures, Anxiety, N/V

Monitoring parameters : arterial or capillary blood gases, Serum theophylline levels

Usual Dose : 300 mg/day in divided doses every 6-8 hours for 3 days then increase to 400 mg/day in divided doses every 6-8 hours for 3 days

Patient Education : Caution in eating or drinking large amounts of caffeine-containing foods or beverages during therapy with this medication

Missed Dose : Taking as soon as possible not taking if almost time for next dose not doubling doses

Auxiliary labels  : May cause drowsiness, Avoid alcoholic beverages, Keep container tightly closed

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